Epidemiological and clinical characteristics of nosocomial candidiasis in university hospitals in Cuiaba - Mato Grosso, Brazil
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
05/11/2013
05/11/2013
2012
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Resumo |
Background: Fungal infections are emerging as an important cause of human disease, especially among hospitalized patients with serious underlying disease and several risk factors. Aims: To evaluate epidemiological and clinical characteristics of patients with nosocomial candidiasis in university hospitals in Cuiaba - MT, Brazil. Methods: A descriptive study of 91 patients admitted to university hospitals in Cuiaba - MT, with clinical and laboratory diagnosis of nosocomial candidiasis, over a 20-month period. Results: A rate for nosocomial infections by Candida spp. of 5 per 1000 admissions, proportional mortality of 14.4% and lethality of 53.8% were determined. The patient age ranged from 29 days to 82 years-old, among which, 74.7% were adults and 25.3% children. The intensive care units contributed with the highest number of cases of infection by Candida spp. (69.2%). The most important underlying disease was gastrointestinal tract disease (11%). Prematurity and low birth weight were the most important risk factors among newborns. The use of antibiotics, invasive procedures, H-2 blockers, multiple blood transfusions and stay length of >= 21 days were the most frequent risk factors among adults. Candida albicans was the most common species in all cases. Conclusions: In this study, C. albicans was the most frequently detected species in candidiasis and risk factors increased the susceptibility of hospitalized patients to acquiring a nosocomial infection by Candida spp. (C) 2011 Revista Iberoamericana de Micologia. Published by Elsevier Espana, S.L. All rights reserved. FAPEMAT Fundacao de Amparo a Pesquisa de Mato Grosso FAPEMAT - Fundacao de Amparo a Pesquisa de Mato Grosso |
Identificador |
REVISTA IBEROAMERICANA DE MICOLOGIA, BILBAO, v. 29, n. 3, supl. 4, Part 1-2, pp. 164-168, 11505, 2012 1130-1406 http://www.producao.usp.br/handle/BDPI/41603 10.1016/j.riam.2012.01.001 |
Idioma(s) |
eng |
Publicador |
ASOCIACION ESPANOLA MICOLOGIA-AEM BILBAO |
Relação |
REVISTA IBEROAMERICANA DE MICOLOGIA |
Direitos |
closedAccess Copyright ASOCIACION ESPANOLA MICOLOGIA-AEM |
Palavras-Chave | #NOSOCOMIAL #RISK FACTORS #CANDIDA SPP. #EPIDEMIOLOGY #TERTIARY CARE HOSPITALS #ANTIFUNGAL SUSCEPTIBILITY #CANDIDEMIA #MYCOLOGY |
Tipo |
article original article publishedVersion |