Analysis of Transmitted Resistance to Raltegravir and Selective Pressure among HIV-1-Infected Patients on a Failing HAART in Sao Paulo, Brazil
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
04/11/2013
04/11/2013
2012
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| Resumo |
We studied the presence of primary resistance to raltegravir (RAL), natural polymorphisms, and selection pressure on HIV-1 integrase. We found a high frequency of integrase polymorphisms related to the resistance to RAL and sequence stability. Further studies are needed to determine the importance of these polymorphisms to RAL resistance. Fundacao de Amparo a Pesquisa do Estado de Sao Paulo Fundacao de Amparo a Pesquisa do Estado de Sao Paulo [09/05712-3] |
| Identificador |
JOURNAL OF CLINICAL MICROBIOLOGY, WASHINGTON, v. 50, n. 6, supl. 4, Part 1, pp. 2122-2125, JUN, 2012 0095-1137 http://www.producao.usp.br/handle/BDPI/37979 10.1128/JCM.00539-12 |
| Idioma(s) |
eng |
| Publicador |
AMER SOC MICROBIOLOGY WASHINGTON |
| Relação |
JOURNAL OF CLINICAL MICROBIOLOGY |
| Direitos |
closedAccess Copyright AMER SOC MICROBIOLOGY |
| Palavras-Chave | #INTEGRASE INHIBITORS #GENETIC DIVERSITY #DRUG-RESISTANCE #NAIVE #SUBTYPES #MICROBIOLOGY |
| Tipo |
article original article publishedVersion |
