Secondary metabolites isolated from Piper chimonantifolium and their antifungal activity


Autoria(s): Lago, Joao Henrique G.; Ito, Alexandre T.; Fernandes, Cesar M.; Young, Maria Claudia M.; Kato, Massuo J.
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

06/11/2013

06/11/2013

2012

Resumo

In this study, the CH2Cl2 extract from leaves of Piper chimonantifolium was subjected to several chromatographic separation procedures to afford one chromene (gaudichaudianic acid) as a major compound as well as two flavonoids (dihydrooroxylin and pinocembrin) and three steroids (sitosterol, sitosteryl palmitate and stigmasterol). The structures of all determined compounds were characterised by spectrometric analysis, mainly mass spectrometry and NMR, as well as their optical properties. This article describes the first phytochemical study of the leaves of P. chimonantifolium and an evaluation of the antifungal activity of its major compounds.

CNPq

CNPq

FAPESP

FAPESP

Identificador

NATURAL PRODUCT RESEARCH, ABINGDON, v. 26, n. 8, pp. 770-773, NOV, 2012

1478-6419

http://www.producao.usp.br/handle/BDPI/42086

10.1080/14786419.2011.561435

http://dx.doi.org/10.1080/14786419.2011.561435

Idioma(s)

eng

Publicador

TAYLOR & FRANCIS LTD

ABINGDON

Relação

NATURAL PRODUCT RESEARCH

Direitos

closedAccess

Copyright TAYLOR & FRANCIS LTD

Palavras-Chave #PIPER CHIMONANTIFOLIUM #CHROMENE #FLAVONOIDS #STEROIDS #ANTIFUNGAL ACTIVITY #CRASSINERVIUM KUNTH #BENZOIC-ACID #CONSTITUENTS #LHOTZKYANUM #DERIVATIVES #LEAVES #LONGUM #CHEMISTRY, APPLIED #CHEMISTRY, MEDICINAL
Tipo

article

original article

publishedVersion