Early postoperative pelvic-floor biofeedback improves erectile function in men undergoing radical prostatectomy: a prospective, randomized, controlled trial


Autoria(s): Prota, C.; Gomes, C. M.; Ribeiro, L. H. S.; de Bessa, J., Jr.; Nakano, E.; Dall'Oglio, M.; Bruschini, H.; Srougi, M.
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

06/11/2013

06/11/2013

2012

Resumo

Erectile dysfunction (ED) and urinary incontinence are common complications following radical prostatectomy (RP). Although pelvic-floor biofeedback training (PFBT) may improve urinary continence following RP, its effects on the recovery of potency are unknown. Fifty-two patients selected for RP were prospectively randomized for a treatment group (n=26) receiving PFBT once a week for 3 months and home exercises or a control group (n=26), in which patients received verbal instructions to contract the pelvic floor. Erectile function (EF) was evaluated with the International Index of Erectile Function-5 (IIEF-5) before surgery and 1, 3, 6 and 12 months postoperatively. Patients were considered potent when they had a total IIEF-5 score >20. Continence status was assessed and defined as the use of no pads. Groups were comparable in terms of age, body mass index, diabetes, pathological tumor stage and neurovascular bundle preservation. A significant reduction in IIEF-5 scores was observed after surgery in both groups. In the treatment group, 8 (47.1%) patients recovered potency 12 months postoperatively, as opposed to 2 (12.5%) in the control group (P=0.032). The absolute risk reduction was 34.6% (95% confidence interval (CI): 3.8-64%) and the number needed to treat was 3 (95% CI: 1.5-17.2). A strong association between recovery of potency and urinary continence was observed, with continent patients having a 5.4 higher chance of being potent (P=0.04). Early PFBT appears to have a significant impact on the recovery of EF after RP. Urinary continence status was a good indicator of EF recovery, with continent patients having a higher chance of being potent.

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP), Brazil

FAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo, Brazil)

Identificador

INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, LONDON, v. 24, n. 5, supl. 1, Part 3, pp. 174-178, SEP-OCT, 2012

0955-9930

http://www.producao.usp.br/handle/BDPI/42049

10.1038/ijir.2012.11

http://dx.doi.org/10.1038/ijir.2012.11

Idioma(s)

eng

Publicador

NATURE PUBLISHING GROUP

LONDON

Relação

INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH

Direitos

closedAccess

Copyright NATURE PUBLISHING GROUP

Palavras-Chave #BIOFEEDBACK #ERECTILE DYSFUNCTION #PROSTATECTOMY #URINARY INCONTINENCE #RETROPUBIC PROSTATECTOMY #SEXUAL FUNCTION #RAT MODEL #NOCTURNAL ERECTIONS #NEUROTROPHIC FACTOR #SILDENAFIL CITRATE #FUNCTION RECOVERY #CANCER OUTCOMES #DOUBLE-BLIND #DYSFUNCTION #UROLOGY & NEPHROLOGY
Tipo

article

original article

publishedVersion