Leucine supplementation combined with resistance exercise improves the plasma lipid profile of dexamethasone-treated rats


Autoria(s): Nicastro, Humberto; Luz, Claudia R da; Chaves, Daniela FS; Neves, Willian das; Valente, Kerolyn S; Lancha Junior, Antonio H
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

06/11/2013

06/11/2013

2012

Resumo

The impact of leucine supplementation and resistance exercise (RE) on plasma lipid profile was evaluated in adult rats treated with dexamethasone, an experimental model of dyslipidemia. Total cholesterol did not differ among groups. Furthermore, leucine supplementation did not promote improvement in the plasma total cholesterol and LDL-c of the animals. However, plasma TG and VLDL-c were significantly decreased and HDL-c increased after 7 days of leucine supplementation combined with RE. In conclusion, leucine supplementation combined with RE, but not isolated, improved the plasma lipid profile of dexamethasone-induced dyslipidemic rats.

FAPESP [10/07062-3, 09/52022-2, 2011/04690-6, 10/110852-60]

Identificador

LIPIDS IN HEALTH AND DISEASE, LONDON, v. 11, JAN 11, 2012

1476-511X

http://www.producao.usp.br/handle/BDPI/42066

10.1186/1476-511X-11-7

http://dx.doi.org/10.1186/1476-511X-11-7

Idioma(s)

eng

Publicador

BIOMED CENTRAL LTD

LONDON

Relação

Lipids in Health and Disease

Direitos

openAccess

Copyright BIOMED CENTRAL LTD

Palavras-Chave #BRANCHED-CHAIN AMINO ACIDS #GLUCOCORTICOID #LIPID PROFILE #EXERCISE #CHOLESTEROL #BIOCHEMISTRY & MOLECULAR BIOLOGY
Tipo

article

original article

publishedVersion