Cerium metal- mediated Reformatsky-type reaction with ethyl bromosuccinate for the synthesis of novel paraconic acid analogs
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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| Data(s) |
06/11/2013
06/11/2013
2012
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| Resumo |
The treatment of cerium metal with ethyl bromosuccinate (1) forms the stabilized organolanthanoid intermediate (2), which reacts with carbonyl compounds in a Reformatsky-type reaction, under mild conditions, to produce functionalized gamma-substituted paraconic acids (4) in good yields. (C) 2012 Elsevier Ltd. All rights reserved. FAPESP FAPESP CNPq CNPq CAPES CAPES |
| Identificador |
TETRAHEDRON LETTERS, OXFORD, v. 53, n. 45, supl. 1, Part 1, pp. 6136-6137, 39387, 2012 0040-4039 http://www.producao.usp.br/handle/BDPI/42298 10.1016/j.tetlet.2012.08.155 |
| Idioma(s) |
eng |
| Publicador |
PERGAMON-ELSEVIER SCIENCE LTD OXFORD |
| Relação |
TETRAHEDRON LETTERS |
| Direitos |
closedAccess Copyright PERGAMON-ELSEVIER SCIENCE LTD |
| Palavras-Chave | #ETHYL BROMOSUCCINATE #CERIUM METAL #REFORMATSKY-TYPE REACTION #PARACONIC ACIDS #LANTHANOID METALS #NATURAL-PRODUCTS #ADDITIONS #REAGENTS #CHEMISTRY, ORGANIC |
| Tipo |
article original article publishedVersion |
