Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyema
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
20/09/2013
20/09/2013
01/12/2012
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Resumo |
OBJECTIVE: Serial C-reactive protein measurements have been used to diagnose and monitor the response to therapy in patients with pneumonia and other infectious diseases. Nonetheless, the role of C-reactive protein measurement after surgical treatment for pleural empyema is not well defined. The aim of this study is to describe the behavior of C-reactive protein levels after the surgical treatment of pleural empyema and to correlate this parameter with the patient's prognosis. METHODS: We retrospectively analyzed the records of patients with pleural empyema treated by either chest-tube drainage or surgery from January 2006 to December 2008. C-reactive protein levels were recorded preoperatively and 2 and 7 days postoperatively. The clinical outcome was binary: success or failure (mortality or the need for repeated pleural intervention). RESULTS: The study group comprised fifty-two patients. The median C-reactive protein values were as follows: 146 mg/L (pre-operative), 134 mg/L (post-operative day 2), and 116 mg/L (post-operative day 7). There was a trend toward a decrease in these values during the first week after surgery, but this difference was only statistically significant on day 7 after surgery. Over the first week after surgery, the C-reactive protein values decreased similarly in both groups (successful and failed treatment). No correlation between the preoperative C-reactive protein level and the clinical outcome was found. CONCLUSIONS: We observed that, in contrast to other medical conditions, C-reactive protein levels fall slowly during the first postoperative week in patients who have undergone surgical treatment for pleural empyema. No correlation between the perioperative C-reactive protein level and the clinical outcome was observed. |
Identificador |
CLINICS, SAO PAULO, v. 67, n. 3, pp. 243-247, DEC 20, 2012 1807-5932 http://www.producao.usp.br/handle/BDPI/33528 10.6061/clinics/2012(03)07 |
Idioma(s) |
eng |
Publicador |
HOSPITAL CLINICAS, UNIV SAO PAULO SAO PAULO |
Relação |
CLINICS |
Direitos |
openAccess Copyright HOSPITAL CLINICAS, UNIV SAO PAULO |
Palavras-Chave | #PLEURAL EMPYEMA #C-REACTIVE PROTEIN #TREATMENT OUTCOME #SURGERY #COMMUNITY-ACQUIRED PNEUMONIA #SEVERITY #UTILITY #MARKER #MEDICINE, GENERAL & INTERNAL |
Tipo |
article original article publishedVersion |