Exploiting the enzymatic machinery of Arthrobacter atrocyaneus for oxidative kinetic resolution of secondary alcohols
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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| Data(s) |
04/11/2013
04/11/2013
2012
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| Resumo |
We evaluated Arthrobacter atrocyaneus (R1AF57) as producer of oxidoreductases for oxidative kinetic resolution of racemic secondary alcohols via oxidation reaction. This bacterium was isolated from Amazon soil samples using medium enriched with (RS)-1-(4-methylphenyl)ethanol as a carbon source. The kinetic resolution of several secondary alcohols through enantioselective oxidation mediated by resting cells and growing cells of A. atrocyaneus was efficiently achieved for the most alcohols. In general, it was possible to obtain only the (S)-enantiomer from (RS)-1-arylethanols. CNPq CNPq CAPES CAPES FAPESP FAPESP |
| Identificador |
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, AMSTERDAM, v. 83, p. 23-28, 2012 1381-1177 http://www.producao.usp.br/handle/BDPI/37774 10.1016/j.molcatb.2012.06.013 |
| Idioma(s) |
eng |
| Publicador |
ELSEVIER SCIENCE BV AMSTERDAM |
| Relação |
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC |
| Direitos |
closedAccess Copyright ELSEVIER SCIENCE BV |
| Palavras-Chave | #ARTHROBACTER ATROCYANEUS #OXIDOREDUCTASES #ALCOHOL DEHYDROGENASE #CHIRAL ALCOHOLS #ENANTIOSELECTIVE REDUCTION #POLYCHLORINATED-BIPHENYLS #ASPERGILLUS-TERREUS #STRAINS #MICROORGANISMS #KETONES #BIOTRANSFORMATIONS #DERACEMIZATION #ACETOPHENONES #BIOREDUCTION #BIOCHEMISTRY & MOLECULAR BIOLOGY #CHEMISTRY, PHYSICAL |
| Tipo |
article original article publishedVersion |
