Burden of maternal bipolar disorder on at-risk offspring: A controlled study on family planning and maternal care


Autoria(s): Moreno, Doris Hupfeld; Bio, Danielle Soares; Petresco, Sandra; Petresco, Denise; Gutt, Elisa Kijner; Soeiro-de-Souza, Marcio Gerhardt; Moreno, Ricardo Alberto
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

01/11/2013

01/11/2013

2012

Resumo

Introduction: Bipolar disorder (BD) is a highly incapacitating disease typically associated with high rates of familial dysfunction. Despite recent literature suggesting that maternal care is an important environmental factor in the development of behavioral disorders, it is unclear how much maternal care is dysfunctional in BD subjects. Objective: The objective of this study was to characterize maternal care in DSM-IV/SCID diagnosed BD type I subjects compared to healthy controls with (PD) and without (NPD) other psychiatric diagnoses. Materials and methods: Thirty-four BD mothers and 106 controls underwent an interview about family planning and maternal care, obstetrical complications, and mother-child interactions. K-SADS-PL questions about violence exposure were used to ascertain domestic violence and physical/sexual abuse. Results: BD mothers were less likely to have stable unions (45.5%; p < 0.01) or to live with the biological father of their children (33.3%; p < 0.01), but had higher educational level and higher rates of social security use/retirement. They also had fewer children and used less contraceptive methods than controls. Children of BD women had higher rates of neonatal anoxia, and reported more physical abuse (16.1%; p = 0.02) than offspring of NPD mothers. Due to BD mothers' symptoms, 33.3% of offspring suffered physical and/or psychological abuse. Limitations: Post hoc analysis, and the use of questions as a surrogate of symptoms as opposed to validated instruments. Conclusion: This is one of few reports confirming that maternal care given by BD women is dysfunctional. BD psychopathology can lead to poor maternal care and both should be considered important environmental risk factors in BD, suggesting that BD psychoeducation should include maternal care orientation. (C) 2012 Elsevier B.V. All rights reserved.

Mood Disorders Unit

Mood Disorders Unit

Identificador

JOURNAL OF AFFECTIVE DISORDERS, AMSTERDAM, v. 143, n. 41334, supl. 1, Part 3, pp. 172-178, DEC 20, 2012

0165-0327

http://www.producao.usp.br/handle/BDPI/37725

10.1016/j.jad.2012.05.050

http://dx.doi.org/10.1016/j.jad.2012.05.050

Idioma(s)

eng

Publicador

ELSEVIER SCIENCE BV

AMSTERDAM

Relação

JOURNAL OF AFFECTIVE DISORDERS

Direitos

closedAccess

Copyright ELSEVIER SCIENCE BV

Palavras-Chave #BIPOLAR DISORDER #PARENTING #MATERNAL CARE #OBSTETRICAL COMPLICATIONS #DEPRESSION #RISK FACTORS #MENTAL-DISORDERS #MOOD DISORDERS #PARENTS #CHILDREN #PREVALENCE #WOMEN #ADOLESCENTS #DEPRESSION #PSYCHOPATHOLOGY #SCHIZOPHRENIA #CLINICAL NEUROLOGY #PSYCHIATRY
Tipo

article

original article

publishedVersion