The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders


Autoria(s): Glotz, Denis; Chapman, Jeremy R.; Dharnidharka, Vikas R.; Hanto, Douglas W.; Castro, Maria C. R.; Hirsch, Hans H.; Leblond, Veronique; Mehta, Aneesh K.; Moulin, Bruno; Pagliuca, Antonio; Pascual, Julio; Rickinson, Alan B.; Russo, Francesco P.; Trappe, Ralf U.; Webster, Angela C.; Zuckermann, Andreas O.; Gross, Thomas G.
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

01/11/2013

01/11/2013

02/08/2013

Resumo

Posttransplant lymphoproliferative disorders (PTLDs) are associated with significant morbidity and mortality among solid-organ transplant patients, but approaches to diagnosis and management vary considerably. An international multidisciplinary panel evaluated current understanding of risk factors and classification systems and developed recommendations to aid in PTLD prevention. We considered evidence on PTLD risk factors including Epstein- Barr virus serostatus and immunosuppression and identified knowledge gaps for future research. Recommendations address prophylactic and preemptive strategies to minimize PTLD development, including modulation of immunosuppression and antiviral drug regimens. Finally, new classification criteria were outlined that may help facilitate standardized reporting and improve our understanding of PTLD.

Genzyme

Genzyme

CSL Behring

CSL Behring

Mundipharma

Mundipharma

Amgen

Amgen

Roche

Roche

BMS

BMS

Pfizer

Pfizer

Astellas

Astellas

Novartis

Novartis

Fresenius

Fresenius

Identificador

TRANSPLANTATION, PHILADELPHIA, v. 94, n. 8, supl. 1, Part 6, pp. 784-793, OCT 27, 2012

0041-1337

http://www.producao.usp.br/handle/BDPI/37386

10.1097/TP.0b013e318269e64f

http://dx.doi.org/10.1097/TP.0b013e318269e64f

Idioma(s)

eng

Publicador

LIPPINCOTT WILLIAMS & WILKINS

PHILADELPHIA

Relação

TRANSPLANTATION

Direitos

closedAccess

Copyright LIPPINCOTT WILLIAMS & WILKINS

Palavras-Chave #EPSTEIN-BARR VIRUS INFECTION #IMMUNOSUPPRESSION #LYMPHOPROLIFERATIVE DISORDER #TRANSPLANTATION #EPSTEIN-BARR-VIRUS #SOLID-ORGAN TRANSPLANTATION #NON-HODGKIN-LYMPHOMA #PEDIATRIC KIDNEY-TRANSPLANTATION #RENAL-TRANSPLANTATION #LIVER-TRANSPLANTATION #RISK-FACTORS #UNITED-STATES #COLLABORATIVE TRANSPLANT #ANTIVIRAL THERAPY #IMMUNOLOGY #SURGERY #TRANSPLANTATION
Tipo

article

original article

publishedVersion