Preliminary in vitro evaluation of N '-(benzofuroxan-5-yl)methylene benzohydrazide derivatives as potential anti-Trypanosoma cruzi agents
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
01/11/2013
01/11/2013
02/08/2013
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| Resumo |
A set of benzofuroxan derivatives was tested in vitro against Trypanosoma cruzi epimastigote forms. The influence of physicochemical properties on these benzofuroxan derivatives' activity was observed, and the presence of electron-withdrawing and hydrophobic groups attached to the benzene ring seems to make a favorable contribution at lower concentrations. CNPq CNPq CAPES CAPES FAPESP FAPESP |
| Identificador |
MEDCHEMCOMM, CAMBRIDGE, v. 3, n. 7, supl. 1, Part 3, pp. 824-828, JUL, 2012 2040-2503 http://www.producao.usp.br/handle/BDPI/37375 10.1039/c2md20019h |
| Idioma(s) |
eng |
| Publicador |
ROYAL SOC CHEMISTRY CAMBRIDGE |
| Relação |
MEDCHEMCOMM |
| Direitos |
openAccess Copyright ROYAL SOC CHEMISTRY |
| Palavras-Chave | #CHAGAS-DISEASE #BENZOFUROXAN DERIVATIVES #STAPHYLOCOCCUS-AUREUS #ASSAY #DESIGN #BIOCHEMISTRY & MOLECULAR BIOLOGY #CHEMISTRY, MEDICINAL |
| Tipo |
article original article publishedVersion |
