The in vitro antioxidant properties of the Al-quercetin/beta CD and Al-catechin/beta CD inclusion compounds, rationalized in terms of their electrochemical behaviour
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
01/11/2013
01/11/2013
02/08/2013
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| Resumo |
Inclusion compounds of Al-quercetin and Al-catechin complexes with beta-cyclodextrin (beta CD) were investigated. The complex and the inclusion compound of quercetin are more effective DPPHaEuro cent scavengers than the corresponding catechin compounds and the inclusion does not compromise their scavenging abilities, with only a slight decrease in the EC50 values. This is in accordance with the electrochemical data, which revealed that the inclusion compounds have lower diffusion coefficients in aqueous solution than the non-included compounds. For the quercetin compounds, some spectroscopic properties were also addressed by means of UV-visible and NMR measurements in aqueous media. Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) Conselho Nacional de Desenvolvimento Cientifico e Tecnologico Conselho Nacional de Desenvolvimento Cientifico e Tecnologico Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) |
| Identificador |
MEDICINAL CHEMISTRY RESEARCH, NEW YORK, v. 21, n. 10, supl. 1, Part 6, pp. 2920-2925, OCT, 2012 1054-2523 http://www.producao.usp.br/handle/BDPI/37159 10.1007/s00044-011-9812-0 |
| Idioma(s) |
eng |
| Publicador |
SPRINGER NEW YORK |
| Relação |
MEDICINAL CHEMISTRY RESEARCH |
| Direitos |
closedAccess Copyright SPRINGER |
| Palavras-Chave | #FLAVONOID COMPLEXES #ANTIOXIDANTS #BETA-CYCLODEXTRIN, INCLUSION COMPOUNDS #OXIDATION POTENTIAL #GRAPHITE-ELECTRODES #CYCLIC VOLTAMMETRY #FLAVONOIDS #CYCLODEXTRIN #COMPLEXES #CHEMISTRY, MEDICINAL |
| Tipo |
article original article publishedVersion |
