Desmodus rotundus and Artibeus spp. bats might present distinct rabies virus lineages
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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| Data(s) |
30/10/2013
30/10/2013
02/08/2013
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| Resumo |
In Brazil, bats have been assigned an increasing importance in public health as they are important rabies reservoirs. Phylogenetic studies have shown that rabies virus (RABV) strains from frugivorous bats Artibeus spp. are closely associated to those from the vampire bat Desmodus rotundus, but little is known about the molecular diversity of RABV in Artibeus spp. The N and G genes of RABV isolated from Artibeus spp. and cattle infected by D. rotundus were sequenced, and phylogenetic trees were constructed. The N gene nucleotides tree showed three clusters: one for D. rotundus and two for Artibeus spp. Regarding putative N amino acid-trees, two clusters were formed, one for D. rotundus and another for Artibeus spp. RABV G gene phylogeny supported the distinction between D. rotundus and Artibeus spp. strains. These results show the intricate host relationship of RABV's evolutionary history, and are invaluable for the determination of RABV infection sources. (C) 2012 Elsevier Editora Ltda. All rights reserved. CAPES CAPES CNPq CNPq |
| Identificador |
BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, SALVADOR, v. 16, n. 6, supl. 1, Part 4, pp. 545-551, NOV-DEC, 2012 1413-8670 http://www.producao.usp.br/handle/BDPI/36730 10.1016/j.bjid.2012.07.002 |
| Idioma(s) |
eng |
| Publicador |
CONTEXTO SALVADOR |
| Relação |
BRAZILIAN JOURNAL OF INFECTIOUS DISEASES |
| Direitos |
openAccess Copyright CONTEXTO |
| Palavras-Chave | #RABIES #BAT #ARTIBEUS SPP. #DESMODUS ROTUNDUS #PHYLOGENY #MOLECULAR EPIDEMIOLOGY #GENETIC-CHARACTERIZATION #SAO-PAULO #MOLECULAR EPIDEMIOLOGY #HEMATOPHAGOUS BATS #BRAZILIAN AMAZON #VAMPIRE BATS #REGION #STATE #IDENTIFICATION #NUCLEOPROTEIN #INFECTIOUS DISEASES |
| Tipo |
article original article publishedVersion |
