Early peri-implant endosseous healing of two implant surfaces placed in surgically created circumferential defects. A histomorphometric and fluorescence study in dogs


Autoria(s): Martins de Barros, Raquel Rezende; Novaes, Arthur Belem, Jr.; Queiroz, Adriana; Goncalves de Almeida, Adriana Luisa
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

01/11/2013

01/11/2013

2012

Resumo

Objective Several implant surfaces are being developed, some in the nanoscale level. In this study, two different surfaces had their early healing properties compared in context of circumferential defects of various widths. Material and methods Six dogs had the mandibular premolars extracted. After 8weeks, four implants were placed equicrestally in each side. One acted as control, while the others were inserted into sites with circumferential defects of 1.0, 1.5 and 2.0mm wide and 5mm deep. A nano-modified surface was used on one side and a micro-rough on the other. Bone markers were administered on the third day after implant placement and then after 1, 2, 4weeks to investigate the bone formation dynamic through fluorescence analysis. Ground sections were prepared from 8-week healing biopsies and histomorphometry was performed. Results The fluorescence evaluation of the early healing showed numerically better results for the nano-modified group; however this trend was not followed by the histomorphometric evaluation. A non-significant numerical superiority of the micro-rough group was observed in terms of vertical bone apposition, defect bone fill, bone-to-implant contact and bone density. In the intra-group analysis, the wider defects showed the worse results while the control sites showed the best results for the different parameters, but without statistical relevance. Conclusion Both surfaces may lead to complete fill of circumferential defects, but the gap width has to be considered as a challenge. The nano-scale modification was beneficial in the early stages of bone healing, but the micro-rough surface showed numerical better outcomes at the 8-week final period.

FAPESP [06/56020-6]

FAPESP

Identificador

CLINICAL ORAL IMPLANTS RESEARCH, HOBOKEN, v. 23, n. 12, supl. 1, Part 3, pp. 1340-1351, DEC, 2012

0905-7161

http://www.producao.usp.br/handle/BDPI/37174

10.1111/j.1600-0501.2011.02357.x

http://dx.doi.org/10.1111/j.1600-0501.2011.02357.x

Idioma(s)

eng

Publicador

WILEY-BLACKWELL

HOBOKEN

Relação

CLINICAL ORAL IMPLANTS RESEARCH

Direitos

restrictedAccess

Copyright WILEY-BLACKWELL

Palavras-Chave #BONE #DEFECT #DENTAL IMPLANTS #FLUORESCENCE #HISTOLOGY #OSSEOINTEGRATION #FRESH EXTRACTION SOCKETS #BONE TISSUE FORMATION #TITANIUM IMPLANTS #CALCIUM-PHOSPHATE #FORMATION ADJACENT #TOOTH EXTRACTION #IMMEDIATE #RABBITS #ROUGH #DENTISTRY, ORAL SURGERY & MEDICINE #ENGINEERING, BIOMEDICAL
Tipo

article

original article

publishedVersion