Good clinical response to methotrexate treatment in a patient with fibroblastic rheumatism


Autoria(s): Paupitz, Juliane Aline; de Carvalho, Jozelio Freire
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

30/10/2013

30/10/2013

02/08/2013

Resumo

Fibroblastic rheumatism (FR) is a rare disease first described by Chaouat (in Rev Rhum Mal Osteoartic 47: 345-351, 1980) and is characterized by a combination of rheumatologic and dermatological manifestations. Rheumatologic features are symmetrical polyarthralgias with joint stiffness, associated with cutaneous nodules and sclerodactyly. Histology shows an increased number of fibroblasts and a marked dermal fibrosis. A large number of treatments have been tried, but all of them have shown an unpredictable effect on FR. We report a Brazilian case of FR showing a good clinical response to methotrexate treatment. This drug may be considered an effective treatment in FR.

Federico Foundation

Federico Foundation

CNPq

CNPq [300665/2009-1]

Identificador

RHEUMATOLOGY INTERNATIONAL, HEIDELBERG, v. 32, n. 6, supl. 4, Part 1-2, pp. 1789-1791, JUN, 2012

0172-8172

http://www.producao.usp.br/handle/BDPI/36921

10.1007/s00296-010-1433-2

http://dx.doi.org/10.1007/s00296-010-1433-2

Idioma(s)

eng

Publicador

SPRINGER HEIDELBERG

HEIDELBERG

Relação

RHEUMATOLOGY INTERNATIONAL

Direitos

closedAccess

Copyright SPRINGER HEIDELBERG

Palavras-Chave #FIBROBLASTIC RHEUMATISM #CUTANEOUS NODULOSIS #FIBROSIS #PEYRONIE'S DISEASE #RHEUMATOLOGY
Tipo

article

original article

publishedVersion