Number of recent sexual partners among blood donors in Brazil: associations with donor demographics, donation characteristics, and infectious disease markers


Autoria(s): Patavino, Giuseppina Maria; de Almeida-Neto, Cesar; Liu, Jing; Wright, David J.; Mendrone-Junior, Alfredo; Lopes Ferreira, Maria Ines; de Freitas Carneiro, Anna Barbara; Custer, Brian; Ferreira, Joao Eduardo; Busch, Michael P.; Sabino, Ester Cerdeira
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

29/10/2013

29/10/2013

02/08/2013

Resumo

BACKGROUND: Brazilian blood centers ask candidate blood donors about the number of sexual partners in the past 12 months. Candidates who report a number over the limit are deferred. We studied the implications of this practice on blood safety. STUDY DESIGN AND METHODS: We analyzed demographic characteristics, number of heterosexual partners, and disease marker rates among 689,868 donations from three Brazilian centers between July 2007 and December 2009. Donors were grouped based on maximum number of partners allowed in the past 12 months for each center. Chi-square and logistic regression analysis were conducted to examine associations between demographic characteristics, number of sex partners, and individual and overall positive markers rates for human immunodeficiency virus (HIV), human T-lymphotropic virus Types 1 and 2, hepatitis B virus, hepatitis C virus, and syphilis. RESULTS: First-time, younger, and more educated donors were associated with a higher number of recent sexual partners, as was male sex in Sao Paulo and Recife (p < 0.001). Serologic markers for HIV and syphilis and overall were associated with multiple partners in Sao Paulo and Recife (p < 0.001), but not in Belo Horizonte (p = 0.05, p = 0.94, and p = 0.75, respectively). In logistic regression analysis, number of recent sexual partners was associated with positive serologic markers (adjusted odds ratio [AOR], 1.2-1.5), especially HIV (AOR, 1.9-4.4). CONCLUSIONS: Number of recent heterosexual partners was associated with HIV positivity and overall rates of serologic markers of sexually transmitted infections. The association was not consistent across centers, making it difficult to define the best cutoff value. These findings suggest the use of recent heterosexual contacts as a potentially important deferral criterion to improve blood safety in Brazil.

National, Heart, Lung, and Blood Institute, National Institutes of Health, Retrovirus Epidemiology Donor Study-II International Component

National, Heart, Lung, and Blood Institute, National Institutes of Health, Retrovirus Epidemiology Donor StudyII International Component

Identificador

TRANSFUSION, MALDEN, v. 52, n. 1, supl. 1, Part 6, pp. 151-159, JAN, 2012

0041-1132

http://www.producao.usp.br/handle/BDPI/36535

10.1111/j.1537-2995.2011.03248.x

http://dx.doi.org/10.1111/j.1537-2995.2011.03248.x

Idioma(s)

eng

Publicador

WILEY-BLACKWELL

MALDEN

Relação

TRANSFUSION

Direitos

closedAccess

Copyright WILEY-BLACKWELL

Palavras-Chave #HUMAN-IMMUNODEFICIENCY-VIRUS #SAO-PAULO #UNITED-STATES #RISK-FACTORS #PREVALENCE #CENTERS #HEALTH #IMPACT #SAFETY #HEMATOLOGY
Tipo

article

original article

publishedVersion