4-Organochalcogenoyl-1H-1,2,3-triazoles: synthesis and functionalization by a nickel-catalyzed Negishi cross-coupling reaction
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
29/10/2013
29/10/2013
2012
|
| Resumo |
A general method for the synthesis of triazoles containing selenium and tellurium was accomplished via a CuCAAC reaction between organic azides and a terminal triple bond, generated by in situ deprotection of the silyl group. The reaction tolerates alkyl and arylazides, with alkyl and aryl substituents directly bonded to the chalcogen atom. The products were readily functionalized by a nickel-catalyzed Negishi cross-coupling reaction, furnishing the aryl-heteroaryl products at the 4-position in good yields. (C) 2012 Elsevier Ltd. All rights reserved. Fundacao de Amparo a Pesquisa do Estado de Sao Paulo [FAPESP07/59404-2, 10/15677-8] Fundacao de Amparo a Pesquisa do Estado de Sao Paulo Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) [300.613/2007-5, 152208/2010-0] |
| Identificador |
TETRAHEDRON LETTERS, OXFORD, v. 53, n. 48, supl. 1, Part 1, pp. 6495-6499, 47058, 2012 0040-4039 http://www.producao.usp.br/handle/BDPI/36558 10.1016/j.tetlet.2012.09.062 |
| Idioma(s) |
eng |
| Publicador |
PERGAMON-ELSEVIER SCIENCE LTD OXFORD |
| Relação |
TETRAHEDRON LETTERS |
| Direitos |
closedAccess Copyright PERGAMON-ELSEVIER SCIENCE LTD |
| Palavras-Chave | #SELENIUM #TELLURIUM #TRIAZOLES #NICKEL #NEGISHI #AZIDE-ALKYNE CYCLOADDITION #ORGANOZINC REAGENTS #TERMINAL ALKYNES #CLICK CHEMISTRY #SOLID-PHASE #TELLURIDES #SELENIUM #SALTS #CHEMISTRY, ORGANIC |
| Tipo |
article original article publishedVersion |
