Generation of second messengers in Plasmodium


Autoria(s): Budu, Alexandre; Garcia, Celia Regina da Silva
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

29/10/2013

29/10/2013

2012

Resumo

Signalling in malaria parasites is a field of growing interest as its components may prove to be valuable drug targets, especially when one considers the burden of a disease that is responsible for up to 500 million infections annually. The scope of this review is to discuss external stimuli in the parasite life cycle and the upstream machinery responsible for translating them into intracellular responses, focussing particularly on the calcium signalling pathway. (C) 2012 Published by Elsevier Masson SAS on behalf of Institut Pasteur.

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)

INCT-InBqmed

INCTInBqmed

Pronex-Malaria (CNPq-FAPESP - DECIT)

PronexMalaria (CNPqFAPESP DECIT)

FAPESP

FAPESP

Identificador

MICROBES AND INFECTION, AMSTERDAM, v. 14, n. 10, Special Issue, supl. 1, Part 4, pp. 787-795, AUG, 2012

1286-4579

http://www.producao.usp.br/handle/BDPI/36416

10.1016/j.micinf.2012.04.012

http://dx.doi.org/10.1016/j.micinf.2012.04.012

Idioma(s)

eng

Publicador

ELSEVIER SCIENCE BV

AMSTERDAM

Relação

MICROBES AND INFECTION

Direitos

closedAccess

Copyright ELSEVIER SCIENCE BV

Palavras-Chave #MALARIA #CELL SIGNALLING #PLASMODIUM #ATP #SECOND MESSENGERS #INTRAERYTHROCYTIC MALARIA PARASITE #FALCIPARUM CELL-CYCLE #RED-BLOOD-CELLS #INFECTED ERYTHROCYTES #SIGNAL-TRANSDUCTION #INTRACELLULAR CA2+ #PHOSPHOLIPASE-C #P-CHABAUDI #CALCIUM #MELATONIN #IMMUNOLOGY #INFECTIOUS DISEASES #MICROBIOLOGY
Tipo

article

original article

publishedVersion