Bioconversion of Iodoacetophenones by Marine Fungi
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
29/10/2013
29/10/2013
2012
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| Resumo |
Nine marine fungi (Aspergillus sclerotiorum CBMAI 849, Aspergillus sydowii Ce19, Beauveria felina CBMAI 738, Mucor racemosus CBMAI 847, Penicillium citrinum CBMAI 1186, Penicillium miczynskii Ce16, P. miczynskii Gc5, Penicillium oxalicum CBMAI 1185, and Trichoderma sp. Gc1) catalyzed the asymmetric bioconversion of iodoacetophenones 1-3 to corresponding iodophenylethanols 6-8. All the marine fungi produced exclusively (S)-ortho-iodophenylethanol 6 and (S)-meta-iodophenylethanol 7 in accordance to the Prelog rule. B. felina CBMAI 738, P. miczynskii Gc5, P. oxalicum CBMAI 1185, and Trichoderma sp. Gc1 produced (R)-para-iodophenylethanol 8 as product anti-Prelog. The bioconversion of para-iodoacetophenone 3 with whole cells of P. oxalicum CBMAI 1185 showed competitive reduction-oxidation reactions. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) USP-Reitoria USPReitoria |
| Identificador |
MARINE BIOTECHNOLOGY, NEW YORK, v. 14, n. 4, supl., Part 3, pp. 396-401, AUG, 2012 1436-2228 http://www.producao.usp.br/handle/BDPI/36285 10.1007/s10126-012-9463-2 |
| Idioma(s) |
eng |
| Publicador |
SPRINGER NEW YORK |
| Relação |
MARINE BIOTECHNOLOGY |
| Direitos |
closedAccess Copyright SPRINGER |
| Palavras-Chave | #IODOPHENYLETHANOLS #MARINE FUNGI #REDUCTION #KETONES #ASPERGILLUS SYDOWII #BIOTRANSFORMATION #METABOLITES #REDUCTION #KETONES #BIOTECHNOLOGY & APPLIED MICROBIOLOGY #MARINE & FRESHWATER BIOLOGY |
| Tipo |
article original article publishedVersion |
