Fast Determination of Ciclopirox in Pharmaceutical Products by Amperometry in Flow and Batch Injection Systems
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
23/10/2013
23/10/2013
2012
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| Resumo |
Amperometry coupled to flow injection analysis (FIA) and to batch injection analysis (BIA) was used for the rapid and precise quantification of ciclopirox olamine in pharmaceutical products. The favourable hydrodynamic conditions provided by both techniques allowed a very high throughput (more than 300 injections per hour) with good linear range (2.0200 mu mol L-1) and low limits of detection (below 1.0 mu mol?L-1). The results obtained were compared with titration recommended by the American Pharmacopoeia and also using capillary electrophoresis. Good agreement between all results were achieved, demonstrating the good performance of amperometry combined with FIA and BIA. Brazilian foundation FAPESP FAPESP, Brazilian Foundation CNPq, Brazilian Foundation [480311-2009-9] Brazilian Foundation CNPq CAPES, Brazilian Foundation Brazilian foundation CAPES |
| Identificador |
ELECTROANALYSIS, WEINHEIM, v. 24, n. 4, Special Issue, pp. 961-966, APR, 2012 1040-0397 http://www.producao.usp.br/handle/BDPI/35552 10.1002/elan.201100713 |
| Idioma(s) |
eng |
| Publicador |
WILEY-V C H VERLAG GMBH WEINHEIM |
| Relação |
ELECTROANALYSIS |
| Direitos |
closedAccess Copyright WILEY-V C H VERLAG GMBH |
| Palavras-Chave | #CICLOPIROX OLAMINE #AMPEROMETRY #FLOW INJECTION ANALYSIS #BATCH INJECTION ANALYSIS #GLASSY CARBON ELECTRODE #VOLTAMMETRIC DETERMINATION #CAPILLARY-ELECTROPHORESIS #PRECOLUMN DERIVATIZATION #OLAMINE #ELECTRODE #CHROMATOGRAPHY #FORMULATIONS #PURE #CHEMISTRY, ANALYTICAL #ELECTROCHEMISTRY |
| Tipo |
article original article publishedVersion |
