Measuring Adherence to Antiretroviral Treatment: The Role of Pharmacy Records of Drug Withdrawals


Autoria(s): Gutierrez, Eliana Battaggia; Christovam Sartori, Ana Marli; Schmidt, Ana Lucia; Piloto, Bruna Mamprim; Franca, Bruna Biagi; de Oliveira, Adriana Santos; Pouza, Adriana Rodrigues; Moreno, Roberta Vilela; Picone, Camila de Melo; Sampaio de Almeida Ribeiro, Manoel Carlos
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

14/10/2013

14/10/2013

2012

Resumo

This study aimed to evaluate adherence to anti-retroviral treatment (ART) among HIV + adults, assess its association with HIV viral load (VL) and identify factors associated to adherence. A survey involving a random sample of adults followed at a HIV/AIDS reference center in Sao Paulo city, Brazil, from 2007 to 2009 was done. A questionnaire was applied and data were retrieved from the pharmacy and medical records. The study involved 292 subjects: 70.2% men; median age: 43 years; median duration of ART: 8 years. 89.3% self-reported taken all prescribed pills in the last 3 days but only 39.3% picked up >= 95% of the prescribed ART from the pharmacy in the last 12 months. At the multivariate analysis having symptoms prior to ART, taking fewer ART pills, and not missing medical appointments were independently associated to higher adherence. Adherence was strongly associated with undetectable HIV VL. Rates of undetectable HIV VL did not differ from 80 to >= 95% of adherence.

Identificador

AIDS AND BEHAVIOR, NEW YORK, v. 16, n. 6, supl. 4, Part 1, pp. 1482-1490, AUG, 2012

1090-7165

http://www.producao.usp.br/handle/BDPI/34493

10.1007/s10461-012-0168-3

http://dx.doi.org/10.1007/s10461-012-0168-3

Idioma(s)

eng

Publicador

SPRINGER/PLENUM PUBLISHERS

NEW YORK

Relação

AIDS AND BEHAVIOR

Direitos

closedAccess

Copyright SPRINGER/PLENUM PUBLISHERS

Palavras-Chave #AIDS #HIV #ANTIRETROVIRAL TREATMENT #ADHERENCE #PHARMACY-BASED MEASURES #SELF-REPORTING #PROTEASE INHIBITOR THERAPY #HIV-INFECTED PATIENTS #LESS-THAN 95-PERCENT #BRAZIL #SUPPRESSION #NONADHERENCE #CHALLENGES #OUTCOMES #PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH #SOCIAL SCIENCES, BIOMEDICAL
Tipo

article

original article

publishedVersion