Molecular epidemiology of the SH (small hydrophobic) gene of human respiratory syncytial virus (HRSV), over 2 consecutive years
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
23/09/2013
23/09/2013
2012
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| Resumo |
Human respiratory syncytial virus (HRSV) strains were isolated from nasopharyngeal aspirates collected from 965 children between 2004 and 2005, yielding 424 positive samples. We sequenced the small hydrophobic protein (SH) gene of 117 strains and compared them with other viruses identified worldwide. Phylogenetic analysis showed a low genetic variability among the isolates but allowed us to classify the viruses into different genotypes for both groups, HRSVA and HRSVB. It is also shown that the novel BA-like genotype was well segregated from the others, indicating that the mutations are not limited to the G gene. (C) 2011 Elsevier B.V. All rights reserved. Brazilian Research Council (CNPq) Brazilian Research Council (CNPq) Research Support Foundation of the State of Sao Paulo, Brazil (FAPESP) FAPESP (Research Support Foundation of the State of Sao Paulo, Brazil) |
| Identificador |
VIRUS RESEARCH, AMSTERDAM, v. 163, n. 1, pp. 82-86, JAN, 2012 0168-1702 http://www.producao.usp.br/handle/BDPI/33578 10.1016/j.virusres.2011.08.013 |
| Idioma(s) |
eng |
| Publicador |
ELSEVIER SCIENCE BV AMSTERDAM |
| Relação |
VIRUS RESEARCH |
| Direitos |
closedAccess Copyright ELSEVIER SCIENCE BV |
| Palavras-Chave | #HRSV #SMALL HYDROPHOBIC PROTEIN #MOLECULAR EPIDEMIOLOGY #G-PROTEIN GENE #SUBGROUP-B #CIRCULATION PATTERNS #GROUP-A #NOSOCOMIAL OUTBREAK #60 NUCLEOTIDES #SOUTH-AFRICA #GENOTYPES #STRAINS #SEASONS #VIROLOGY |
| Tipo |
article original article publishedVersion |
