Structure and antimycobacterial activity of the novel organometallic [Pd(C-bzan)(SCN)(dppp)] compound
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
13/09/2013
13/09/2013
2012
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| Resumo |
The organometallic compound [Pd(C-bzan)(SCN)(dppp)] {bzan = N-benzylideneaniline, dppp = 1,3-bis(diphenylphosphino)propane} was synthesized and characterized by elemental analyses, infrared and H-1 and P-31(H-1) NMR spectroscopies. The crystal and molecular structures of the title complex were determined by single-crystal X-ray diffraction techniques. In vitro antimycobacterial evaluation demonstrated that the compound [Pd(C-bzan)(SCN)(dppp)] displayed a MIC of 5.15 mu M, which is superior than those values found for some commonly used anti-TB drugs and other Pd(II) complexes. (C) 2012 Elsevier B.V. All rights reserved. CNPq CNPq FAPESP FAPESP CAPES CAPES |
| Identificador |
INORGANIC CHEMISTRY COMMUNICATIONS, AMSTERDAM, v. 23, n. 1, supl. 4, Part 1-2, pp. 63-66, SEP, 2012 1387-7003 http://www.producao.usp.br/handle/BDPI/33335 10.1016/j.inoche.2012.06.007 |
| Idioma(s) |
eng |
| Publicador |
ELSEVIER SCIENCE BV AMSTERDAM |
| Relação |
INORGANIC CHEMISTRY COMMUNICATIONS |
| Direitos |
closedAccess Copyright ELSEVIER SCIENCE BV |
| Palavras-Chave | #ORGANOMETALLIC PD(II) COMPOUND #1,3-BIS(DIPHENYLPHOSPHINO)PROPANE #MYCOBACTERIUM TUBERCULOSIS #IN-VITRO CYTOTOXICITY #ALAMAR BLUE ASSAY #PALLADIUM(II) COMPLEXES #MYCOBACTERIUM-TUBERCULOSIS #CYCLOPALLADATED COMPLEX #CRYSTAL-STRUCTURE #COORDINATION-COMPOUNDS #MOLECULAR-STRUCTURE #LIGANDS #MONONUCLEAR #CHEMISTRY, INORGANIC & NUCLEAR |
| Tipo |
article original article publishedVersion |
