Malignant epitheliod hemangioendothelioma of the thyroid: a case report


Autoria(s): França, Mariana M.; Souza, Gregório L.; Frank, Michell; Fabris, Viciany Erique; Tagliarini, José Vicente; Mazeto, Gláucia
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

01/04/2016

01/04/2016

2011

Resumo

Primary malignant epithelioid hemangioendothelioma (MEH) of the thyroid is a rare neoplasia with only a few cases reported in the literature. We report a 75 year old man, who presented with a substernal goiter and compressive symptoms. Ultrasonographic evaluation revealed a hypoechogenic nodule in the left lobe, measuring 4.1 cm in maximum diameter, and associated gross calcifications. Fine needle aspiration yielded hemorrhagic material. A left thyroid lobectomy and isthmusectomy was performed. The surgical specimen contained a malignant epithelioid hemangioendothelioma measuring 6 x 4 x 3 cm that had infiltrated about 50% of the thyroidal parenchyma, and surrounded a necrotic nodule. Immunohistochemistry results corroborated the histopathological findings; staining was positive for AE1/AE3, CD31, CD34, factor VIII-related antigen, and Ki-67 expression. Because of the patient’s comorbidities, surgical complementation was not undertaken and he has been undergoing conservative treatment.

Formato

29-31

Identificador

http://globalscienceresearchjournals.org/mcscr/malignant-epithelioid-hemangioendothelioma-of-the-thyroid-a-case-report

Clinical Case Studies, v. 2, n. 2, p. 29-31, 2011.

1534-6501

http://hdl.handle.net/11449/136976

8878595413452908

9224380586557664

Idioma(s)

eng

Relação

Clinical Case Studies

Direitos

closedAccess

Palavras-Chave #Thyroid nodules #Hemangioendothelioma #Goiter #Rare neoplasia
Tipo

info:eu-repo/semantics/article