Delayed tooth replantation in rats: effect of systemic antibiotic therapy with amoxicillin and tetracycline


Autoria(s): Gomes, Weglis Dyanne de Souza; Silva, Cristina Antoniali; Melo, Moriel Evangelista; Silva, Vanessa Ferreira da; Almeida, Melyna Marques de; Pedrini, Denise; Poi, Wilson Roberto; Sonoda, Celso Koogi; Panzarini, Sônia Regina
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

07/12/2015

07/12/2015

31/08/2015

Resumo

Systemic antibiotic therapy (SAT) has usually been recommended after tooth replantation, but its actual value has been questioned. As there are no reports in the literature about its influence on tooth replantation, the aim of this study was to evaluate the influence of systemic administration of antibiotics (amoxicillin and tetracycline) at the different phases of the repair process (7, 15, 30 days) in delayed rat tooth replantation. Ninety Wistar rats (Rattus norvegicus albinus) had their maxillary right incisors extracted and bench-dried for 60 min. The dental papilla, enamel organ, pulp tissue, and root surface-adhered periodontal ligament were removed, and the teeth were replanted. The animals received no antibiotics (n = 30) or were medicated systemically with amoxicillin (n = 30) and tetracycline (n = 30), and were euthanized after 7, 15, and 30 days. Regardless of the evaluation period, the acute inflammatory infiltrate was less intense and root resorption presented smaller extent and depth in the group treated with amoxicillin. The results suggest that SAT has a positive influence on the repair process in delayed tooth replantation and that amoxicillin is an excellent treatment option.

Formato

448-456

Identificador

http://dx.doi.org/10.1111/edt.12207

Dental Traumatology : Official Publication Of International Association For Dental Traumatology, 2015.

1600-9657

http://hdl.handle.net/11449/131543

10.1111/edt.12207

26332890

Idioma(s)

eng

Publicador

Wiley-Blackwell

Relação

Dental Traumatology : Official Publication Of International Association For Dental Traumatology

Direitos

closedAccess

Palavras-Chave #Amoxicillin #Delayed tooth replantation #Root resorption #Tetracycline
Tipo

info:eu-repo/semantics/article