Clinical Assessment of Tribulus terrestris Extract in the Treatment of Female Sexual Dysfunction


Autoria(s): Gama, Carlos R. B.; Lasmar, Ricardo; Gama, Gustavo F.; Abreu, Camila S.; Nunes, Carlos P.; Geller, Mauro; Oliveira, Lisa; Santos, Alessandra
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

07/12/2015

07/12/2015

2014

Resumo

This is a qualitative-quantitative study based on hospital records of female patients of reproductive age, presenting sexual dysfunction, and treated with 250 mg Tribulus terrestris extract (1 tablet thrice daily for 90 days). Safety monitoring included vital signs, physical examination, laboratory tests, and occurrence of adverse events. Efficacy analysis included results of the Female Sexual Function Index (FSFI), dehydroepiandrosterone (DHEA) levels together with total and free testosterone, and the patient and physician assessments. There was a statistically significant improvement in total FSFI scores (P < 0.0001) post-treatment, with improvement among 106 (88.33%) subjects. There was a statistically significant (P < 0.0001) increase in the level of DHEA, while the levels of both serum testosterone (P = 0.284) and free testosterone decreased (P < 0.0001). Most adverse events recorded were related to the gastrointestinal tract. Physical examination showed no significant changes post-treatment. Based on the results, it is concluded that the T. terrestris extract is safe and effective in the treatment of female sexual dysfunction.

Formato

45-50

Identificador

http://dx.doi.org/10.4137/CMWH.S17853

Clinical Medicine Insights. Women's Health, v. 7, p. 45-50, 2014.

1179-562X

http://hdl.handle.net/11449/130974

10.4137/CMWH.S17853

PMC4275110.pdf

25574150

PMC4275110

Idioma(s)

eng

Publicador

Libertas Academica Ltd

Relação

Clinical Medicine Insights. Women's Health

Direitos

openAccess

Palavras-Chave #Tribulus terrestris #Female sexual dysfunction #Female sexual function index
Tipo

info:eu-repo/semantics/article