Bispectral index in calves anesthetized with xylazine, midazolam, ketamine, isoflurane and subjected to continuous rate infusion of lidocaine


Autoria(s): Araújo, Marcelo Augusto de; Beloti, Carolina Aparecida Carlin (UNESP); Deschk, Maurício (UNESP); Arruda, André Moreira Martins; Cheng, Lu Shi; Albuquerque, Verônica Batista de; Santos, Paulo Sergio Patto dos (UNESP)
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

26/08/2015

26/08/2015

01/01/2015

Resumo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Processo FAPESP: 2008/07555-0

Processo FAPESP: 2009/08879-6

PURPOSE: To assess the bispectral index (BIS) and recovery in calves anesthetized with xylazine, midazolam, ketamine and isoflurane and subjected to CRI of lidocaine. METHODS: Xilazine was administered followed by ketamine and midazolam, orotracheal intubation and maintenance on isoflurane using mechanical ventilation. Lidocaine (2 mg kg-1 bolus) or saline (0.9%) was administered IV followed by a CRI (100 µg kg-1 minute-1) of lidocaine (L) or saline (C). Were recorded BIS, heart rate (HR), mean arterial pressure (MAP) and rectal temperature (RT) before administration of premedication (TB) and 15 minutes after (TX), before administering lidocaine (T0) and 20, 40, 60 and 80 minutes after the start of the CRI . Time do sternal recumbency (SRE) and standing (ST) and plasma lidocaine concentration also evaluated. RESULTS: In both treatments BIS decreased significantly at all times compared to TB. TX was higher than the subsequent times. HR decreased from baseline at all times and decreased from T40 in L compared to C. SRE was higher in L compared to C. CONCLUSIONS: Bispectral index values were consistent with the degree of hypnosis of the animals. Lidocaine did not potentiate isoflurane anesthesia assessed by BIS in unstimulated calves anesthetized with constant E´Iso. Lidocaine increased the time to sternal recumbency.

Formato

67-72

Identificador

http://www.scielo.br/scielo.php?pid=S0102-86502015000100067&script=sci_arttext

Acta Cirurgica Brasileira, v. 30, n. 1, p. 67-72, 2015.

0102-8650

http://hdl.handle.net/11449/127318

http://dx.doi.org/10.1590/S0102-86502015001000009

S0102-86502015000100067

S0102-86502015000100067.pdf

Idioma(s)

eng

Publicador

Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia

Relação

Acta Cirurgica Brasileira

Direitos

openAccess

Palavras-Chave #Anesthesia, inhalation #Intermittent positive-pressure ventilation #Anesthesia recovery period #Chromatography #Cattle
Tipo

info:eu-repo/semantics/article