Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
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Data(s) |
18/03/2015
18/03/2015
01/01/2014
|
Resumo |
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, have improved over the past few decades; however, they remain far from optimal. Currently, cancer research is focused on improving cancer diagnosis and treatment methods (oral cavity and oropharynx) nanotechnology, which involves the design, characterization, production, and application of nanoscale drug delivery systems. In medicine, nanotechnologies, such as polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, gold nanoparticles, hydrogels, cyclodextrin complexes, and liquid crystals, are promising tools for diagnostic probes and therapeutic devices. The objective of this study is to present a systematic review of nanotechnology-based drug delivery systems for oral cancers. |
Formato |
3719-3735 |
Identificador |
http://dx.doi.org/10.2147/IJN.S61670 International Journal Of Nanomedicine. Albany: Dove Medical Press Ltd, v. 9, p. 3719-3735, 2014. 1178-2013 http://hdl.handle.net/11449/117454 10.2147/IJN.S61670 WOS:000340169100002 WOS000340169100002.pdf |
Idioma(s) |
eng |
Publicador |
Dove Medical Press Ltd |
Relação |
International Journal Of Nanomedicine |
Direitos |
openAccess |
Palavras-Chave | #targeted delivery #oral squamous cell carcinoma #oral cancer treatment |
Tipo |
info:eu-repo/semantics/article |