Low toxic effects of a whitening strip to cultured pulp cells
Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
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Data(s) |
03/12/2014
03/12/2014
01/10/2013
|
Resumo |
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Processo FAPESP: 11/12938-8 Processo FAPESP: 11/09385-7 Purpose: To assess the trans-enamel and trans-dentin toxicity of a 10% hydrogen peroxide (HP) whitening strip to odontoblast-like cells (MDPC-23). Methods: Enamel surfaces of enamel/dentin discs adapted to artificial pulp chambers were subjected to two 30-minute whitening strip applications to obtain indirect extracts (DMEM + bleaching components that diffused across enamel and dentin). The extracts were applied for 1 hour to the cells for 1 or 5 days. A bleaching gel with 35% HP was used as the positive control. Cell viability (MTT assay) and morphology (SEM) as well as the quantity of HP in the extracts were assessed. Results: Discrete cell viability reduction (21.9%) associated with slight alterations in cell morphology occurred after application of the extracts for 5 days to the MDPC-23 cells (Tukey's test P< 0.05). Lower enamel/dentin diffusion of HP was observed after the use of the whitening strip compared with the bleaching gel (Mann-Whitney P< 0.05). |
Formato |
283-285 |
Identificador |
http://www.amjdent.com/Archive/Abstracts/2013/October%202013%20Abstracts.html#Soares American Journal of Dentistry. Weston: Mosher & Linder, Inc, v. 26, n. 5, p. 283-285, 2013. 0894-8275 http://hdl.handle.net/11449/112548 WOS:000326905700009 |
Idioma(s) |
eng |
Publicador |
Mosher & Linder, Inc |
Relação |
American Journal of Dentistry |
Direitos |
closedAccess |
Tipo |
info:eu-repo/semantics/article |