Caracterização do tratamento medicamentoso com estatinas em unidade básica de saúde
Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
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Data(s) |
27/05/2014
27/05/2014
07/05/2013
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Resumo |
Study Model: Retrospective study. Study Objective: To characterize statin treatment management due to lipid alterations and side effects throughout statin treatment in basic healthcare unit. Methods: Medical reports of women from a basic healthcare unit were analyzed, obtaining: disease presence, regular medication prescription, statin type and dosage, biochemical exams results, musculoskeletal complaints, and statin use cessation, going back the information until the medical consultation of first prescription. Results: Prescribed statins were Simvastatin and Atorvastatin at low doses (10-20 mg). Dose (48,4%) and/or type (25,4%) alterations occurred for lipid profile adequacy. Lipid levels were reduced without creatine kinase elevation. Treatment withdrawn (30,6%) was mainly due to their own decision (74%), which was strongly associated with records of musculoskeletal complaints (Odds Ratio: 6,40[1,53-26,78]). Conclusion: Statin treatment was effective in reducing serum lipid levels and self-reported pain was underestimated, characterizing the major limiting factor for treatment adherence. |
Formato |
47-55 |
Identificador |
Medicina (Brazil), v. 46, n. 1, p. 47-55, 2013. 0076-6046 2176-7262 http://hdl.handle.net/11449/75368 2-s2.0-84876964265 |
Idioma(s) |
por |
Relação |
Medicina (Brazil) |
Direitos |
openAccess |
Palavras-Chave | #Dyslipidemias #HMG-CoA #Medication therapy management #Public health #Statins #atorvastatin #creatine kinase #lipid #simvastatin #consultation #creatine kinase blood level #disease association #disorders of lipid and lipoprotein metabolism #drug withdrawal #female #health care facility #human #lipid analysis #lipid blood level #low drug dose #medical information #musculoskeletal disease #prescription #retrospective study |
Tipo |
info:eu-repo/semantics/article |