Caracterização do tratamento medicamentoso com estatinas em unidade básica de saúde


Autoria(s): Bonfim, Mariana R.; Oliveira, Acary S. B.; Amaral, Sandra Lia do; Monteiro, Henrique Luiz
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

27/05/2014

27/05/2014

07/05/2013

Resumo

Study Model: Retrospective study. Study Objective: To characterize statin treatment management due to lipid alterations and side effects throughout statin treatment in basic healthcare unit. Methods: Medical reports of women from a basic healthcare unit were analyzed, obtaining: disease presence, regular medication prescription, statin type and dosage, biochemical exams results, musculoskeletal complaints, and statin use cessation, going back the information until the medical consultation of first prescription. Results: Prescribed statins were Simvastatin and Atorvastatin at low doses (10-20 mg). Dose (48,4%) and/or type (25,4%) alterations occurred for lipid profile adequacy. Lipid levels were reduced without creatine kinase elevation. Treatment withdrawn (30,6%) was mainly due to their own decision (74%), which was strongly associated with records of musculoskeletal complaints (Odds Ratio: 6,40[1,53-26,78]). Conclusion: Statin treatment was effective in reducing serum lipid levels and self-reported pain was underestimated, characterizing the major limiting factor for treatment adherence.

Formato

47-55

Identificador

http://revista.fmrp.usp.br/2013/vol46n1/DClin_Caracteriza%E7%E3o%20do%20tratamento%20medicamentoso%20com%20estatinas%20em%20unidade%20b%E1sica%20de%20sa%FAde.pdf

Medicina (Brazil), v. 46, n. 1, p. 47-55, 2013.

0076-6046

2176-7262

http://hdl.handle.net/11449/75368

2-s2.0-84876964265

Idioma(s)

por

Relação

Medicina (Brazil)

Direitos

openAccess

Palavras-Chave #Dyslipidemias #HMG-CoA #Medication therapy management #Public health #Statins #atorvastatin #creatine kinase #lipid #simvastatin #consultation #creatine kinase blood level #disease association #disorders of lipid and lipoprotein metabolism #drug withdrawal #female #health care facility #human #lipid analysis #lipid blood level #low drug dose #medical information #musculoskeletal disease #prescription #retrospective study
Tipo

info:eu-repo/semantics/article