Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune


Autoria(s): De Paula Antunes, João Marcelo Azevedo; Megid, Jane
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

27/05/2014

27/05/2014

01/05/2013

Resumo

Brucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection.

Formato

1301-1312

Identificador

http://dx.doi.org/10.5433/1679-0359.2013v34n3p1301

Semina:Ciencias Agrarias, v. 34, n. 3, p. 1301-1312, 2013.

1676-546X

1679-0359

http://hdl.handle.net/11449/75322

10.5433/1679-0359.2013v34n3p1301

WOS:000328267900035

2-s2.0-84880192009

2-s2.0-84880192009.pdf

Idioma(s)

por

Relação

Semina: Ciências Agrárias

Direitos

openAccess

Palavras-Chave #Brucella ovis #Brucellosis #Immunopathology #Pathogenesis
Tipo

info:eu-repo/semantics/article