AC biosusceptometry as a method for measuring gastric contraction
Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
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Data(s) |
27/05/2014
27/05/2014
01/12/2010
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Resumo |
the aim of this study was to validate the Alternate Current Biosusceptometry (ACB) for monitoring gastric contractions in rats. In vitro data were obtained to establish the relationship between ACB and the strain-gauge (SG) signal amplitude. In vivo experiments were performed on rats with magnetic markers and SGs previously implanted under the gastric serosa. The effects of the prandial state in gastric motility profiles were obtained. The correlation between in vitro signal amplitudes was strong (R = 0.989). The temporal cross-correlation between the ACB and SG signal amplitude was higher in the postprandial than in the fasting state. Irregular signal profiles, low contraction amplitudes, and smaller signal-to-noise ratios explained the poor correlation for fasting-state recordings. The contraction frequencies using ACB were 0.068 ± 0.007 Hz (postprandial) and 0.058 ± 0.007 Hz (fasting) and those using SG were 0.066 ± 0.006 Hz (postprandial) and 0.059 ± 0.008 Hz (fasting) (P < 0.003). When a magnetic tracer was ingested, there was a strong correlation and a small phasedifference between techniques. We conclude that ACB provides an accurate and sensitive technique for studies of GI motility in the rat. © 2010 IEEE. |
Formato |
5740-5743 |
Identificador |
http://dx.doi.org/10.1109/IEMBS.2010.5627855 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10, p. 5740-5743, 2010. http://hdl.handle.net/11449/72042 10.1109/IEMBS.2010.5627855 WOS:000287964006035 2-s2.0-78650822764 |
Idioma(s) |
eng |
Relação |
2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 |
Direitos |
closedAccess |
Palavras-Chave | #Alternate current biosusceptometry #Biosusceptometry #Contraction frequency #Cross correlations #Gastric motility #In-vivo experiments #Magnetic marker #Phase difference #Sensitive techniques #Signal amplitude #Strong correlation #Signal to noise ratio |
Tipo |
info:eu-repo/semantics/conferencePaper |