Evaluation of bone ingrowth into porous titanium implant: Histomorphometric analysis in rabbits


Autoria(s): de Vasconcellos, Luana Marotta Reis; Leite, Daniel Oliveira; de Oliveira, Fernanda Nascimento; Carvalho, Yasmin Rodarte; Cairo, Carlos Alberto Alves
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

27/05/2014

27/05/2014

01/10/2010

Resumo

A porous material for bone ingrowth with adequate pore structure and appropriate mechanical properties has long been sought as the ideal bone-implant interface. This study aimed to assess in vivo the influence of three types of porous titanium implant on the new bone ingrowth. The implants were produced by means of a powder metallurgy technique with different porosities and pore sizes: Group 1 = 30% and 180 μm; Group 2 = 30% and 300 μm; and Group 3 = 40% and 180 μm. Six rabbits received one implant of each type in the right and left tibiae and were sacrificed 8 weeks after surgery for histological and histomor-phometric analyses. Histological analysis confirmed new bone in contact with the implant, formed in direction of pores. Histomorphometric evaluation demonstrated that the new bone formation was statistically significantly lower in the group G1 than in group G3, (P = 0.023). Based on these results, increased porosity and pore size were concluded to have a positive effect on the amount of bone ingrowth.

Formato

399-405

Identificador

http://dx.doi.org/10.1590/S1806-83242010000400005

Brazilian Oral Research, v. 24, n. 4, p. 399-405, 2010.

1806-8324

1807-3107

http://hdl.handle.net/11449/71905

10.1590/S1806-83242010000400005

S1806-83242010000400005

2-s2.0-78650629148

2-s2.0-78650629148.pdf

Idioma(s)

eng

Relação

Brazilian Oral Research

Direitos

openAccess

Palavras-Chave #Medical #Osseointegration #Porosity #Titanium #Topography #biomaterial #titanium #animal #bone development #bone regeneration #implant #materials testing #particle size #physiology #porosity #powder #rabbit #scanning electron microscopy #surface property #tibia #Animals #Coated Materials, Biocompatible #Implants, Experimental #Materials Testing #Microscopy, Electron, Scanning #Osteogenesis #Particle Size #Powders #Rabbits #Surface Properties #Tibia
Tipo

info:eu-repo/semantics/article