Efeitos da angiotensina II no sistema cardiovascular


Autoria(s): Trapp, S. M.; Vailati, M. C F; Matsubara, Beatriz Bojikian; Schwartz, D. S.
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

27/05/2014

27/05/2014

01/12/2009

Resumo

Angiotensin is an important peptide of renin-angiotensin-aldosterone system. This peptide has an important function on arterial blood pressure regulation and body fluid homeostasis. However, its action on abnormal conditions causes deleterious effects on the cardiovascular system. Vascular resistance, hypertension, vascular and myocytes hipertrophy, production of free radicals and pro-inflammatory substances are some of the actions of angiotensin II that can result on cardiovascular remodeling. Angiotensinconverting enzyme (ACE) inhibitors, angiotensin receptors antagonists, antiinflammatories and antioxidants are used clinically and/or experimentally to prevent or reduce the effects of angiotensin II. The purpose of this work is to review the actions and interactions of angiotensin II on the cardiovascular system, as well as the therapeutic measures employed for the control of these effects.

Formato

233-243

Identificador

http://ojs.c3sl.ufpr.br/ojs/index.php/veterinary/article/view/16042

Archives of Veterinary Science, v. 14, n. 4, p. 233-243, 2009.

1517-784X

http://hdl.handle.net/11449/71399

2-s2.0-77955151145

2-s2.0-77955151145.pdf

Idioma(s)

por

Relação

Archives of Veterinary Science

Direitos

openAccess

Palavras-Chave #Angiotensin II #Blood vessels #Heart #Hypertension
Tipo

info:eu-repo/semantics/article