Infarto do miocárdio experimental em ratos: Análise do modelo
Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
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Data(s) |
27/05/2014
27/05/2014
01/10/2009
|
Resumo |
One of the most often used strategies to study the physiopathological alterations caused by coronary occlusion is the use of the experimental infarction model in rats. Among other factors, this is due to the similarities in the physiopathological alterations that occur after the infarction in humans. One must consider, however, that this model has characteristics that can hinder the use as well as the interpretation of eventual outcomes. Thus, this review aims at analyzing the main characteristics of the experimental infarction model in rats, discussing the coronary occlusion technique, the consequences and the methods of morphological and functional assessment of the infarction and its clinical implications. |
Identificador |
http://dx.doi.org/10.1590/S0066-782X2009001000018 Arquivos Brasileiros de Cardiologia, v. 93, n. 4, 2009. 0066-782X 1678-4170 http://hdl.handle.net/11449/71173 10.1590/S0066-782X2009001000018 S0066-782X2009001000018 2-s2.0-73449138748 2-s2.0-77954701471 2-s2.0-73449138748.pdf |
Idioma(s) |
spa por eng |
Relação |
Arquivos Brasileiros de Cardiologia |
Direitos |
openAccess |
Palavras-Chave | #Animals, laboratory #Coronary occlusion #Myocardial infarction #Rats #animal experiment #animal model #controlled study #heart failure #heart infarction #heart size #heart surgery #heart ventricle hypertrophy #mortality #muscle cell #nonhuman #rat #review |
Tipo |
info:eu-repo/semantics/article |