Amphibian secretions for drug discovery studies: A search for new antiparasitic and antifungal compounds
| Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
|---|---|
| Data(s) |
27/05/2014
27/05/2014
10/01/2007
|
| Resumo |
The antiparasitic and antifungal activities of nine amphibian skin secretions were studied in different in vitro models. Seven secretions presented a considerable antiprotozoan activity and one showed promising results against Candida sp. These results can be the basis for the development of new drugs, especially for neglected parasitic diseases. © 2007 Bentham Science Publishers Ltd. |
| Formato |
67-73 |
| Identificador |
http://dx.doi.org/10.2174/157018007778992856 Letters in Drug Design and Discovery, v. 4, n. 1, p. 67-73, 2007. 1570-1808 http://hdl.handle.net/11449/69512 10.2174/157018007778992856 WOS:000242910300012 2-s2.0-33845967153 |
| Idioma(s) |
eng |
| Relação |
Letters in Drug Design and Discovery |
| Direitos |
closedAccess |
| Palavras-Chave | #Amphibians #Antimicrobial #Leishmania #Peptides #Secretions #Trypanosoma #amino acid oxidase #amphibian protein #antifungal agent #antiparasitic agent #benznidazole #meglumine antimonate #pentamidine #pyrimethamine #Amphibia #animal cell #animal experiment #animal model #animal tissue #Candida #controlled study #dose response #drug design #drug effect #drug research #enzyme activity #growth inhibition #mouse #nonhuman #priority journal #skin secretion |
| Tipo |
info:eu-repo/semantics/article |
