New bioactive metabolites produced by Phomopsis cassiae, an endophytic fungus in Cassia spectabilis
| Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
|---|---|
| Data(s) |
27/05/2014
27/05/2014
01/11/2005
|
| Resumo |
Two new metabolites, ethyl 2,4-dihydroxy-5,6-dimethylbenzoate (1) and phomopsilactone (2) were isolated from Phomopsis cassiae, an endophytic fungus in Cassia spectabilis. Their structures were elucidated by 1D and 2D NMR, MS and IR spectral data. Compounds 1 and 2 displayed strong antifungal activity against the phytopatogenic fungi Cladosporium cladosporioides and C. sphaerospermum, as well as cytotoxicity against human cervical tumor cell line (HeLa), in in vitro assays. ©2005 Sociedade Brasileira de Química. |
| Formato |
1463-1466 |
| Identificador |
http://dx.doi.org/10.1590/S0103-50532005000800029 Journal of the Brazilian Chemical Society, v. 16, n. 6 B, p. 1463-1466, 2005. 0103-5053 http://hdl.handle.net/11449/68473 10.1590/S0103-50532005000800029 S0103-50532005000800029 WOS:000234078700029 2-s2.0-30844445632 2-s2.0-30844445632.pdf |
| Idioma(s) |
eng |
| Relação |
Journal of the Brazilian Chemical Society |
| Direitos |
openAccess |
| Palavras-Chave | #Antifungal activity #Cassia spectabilis #Cytotoxic metabolites #Endophytic fungi #Phomopsis cassiae |
| Tipo |
info:eu-repo/semantics/article |
