Refining the intestinal motility test in mice to reduce animal stress


Autoria(s): Marona, H. R N; Lucchesi, M. B B
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

27/05/2014

27/05/2014

01/12/2003

Resumo

A new protocol using 3-h fast animal for intestinal motility test was developed in our laboratory aiming the 3R's concept to reduce the stress of animals. Our results may aid in formulating recommendations that can be included in revised guidelines with regard to fasting time of mice.

Formato

79-82

Identificador

Revista de Ciencias Farmaceuticas, v. 24, n. 1, p. 79-82, 2003.

0101-3793

http://hdl.handle.net/11449/67582

2-s2.0-4644251922

Idioma(s)

eng

Relação

Revista de Ciencias Farmaceuticas

Direitos

closedAccess

Palavras-Chave #Animal welfare #In vivo test #Intestinal motility #Loperamide #Mice #loperamide #animal experiment #animal model #animal stress #animal testing reduction #animal testing refinement #animal testing replacement #animal tissue #animal welfare #clinical protocol #controlled study #diagnostic test #diet restriction #function test #in vivo study #intestine motility #intestine motility test #mouse #mouse strain #nonhuman #practice guideline #stress
Tipo

info:eu-repo/semantics/article