The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability


Autoria(s): Ribeiro de Vasconcelos, Ana Tereza; De Almeida, Darcy F.; Hungria, Mariangela; Guimarães, Claudia Teixeira; Antônio, Regina Vasconcellos; Cunha Almeida, Francisca; De Almeida, Luiz G. P.; De Almeida, Rosana; Alves-Gomes, José Antonio; Mazoni Andrade, Elizabeth; Araripe, Julia; De Araújo, Magnolia Fernandes Florencio; Astolfi-Filho, Spartaco; Azevedo, Vasco; Baptistà, Alessandra Jorge; Mendes Bataus, Luiz Artur; Da Silva Batista, Jacqueline; Beló, André; Van den Berg, Cássio; Bogo, Mauricio; Bonatto, Sandro; Bordignon, Juliano; Macedo Brigidom, Marcelo; Alves Brito, Cristiana; Brocchi, Marcelo; Burity, Helio Almeida; Aranha Camargo, Anamaria; De Paula Cardoso, Divina das Dores; Carneiro, Newton Portilho; Carraro, Dirce Maria; Carvalho, Cláudia Márcia Benedetto; De Mattos Cascardo, Júlio Cézar; Sousa Cavada, Benildo; Chueire, Ligia Maria O.; Beatriz Creczynski-Pasa, Tânia; Costa Da Cunha-Junior, Nivaldo; Fagundes, Nelson; Lima Falão, Clarissa; Fantinatti, Fabiana; Farias, Izeni Pires; Felipe, Maria Sueli Soares; Pereira Ferrari, Lilian; Aparecido Ferro, Jesus; Tiraboschi Ferro, Maria Inès; Franco, Gloria Regina; Aguiar de Freitas, Nara Suzy; Furlan, Luiz Roberto; Tostes Gazzinelli, Ricardo; Aparecida Gomes, Eliane; Rodrigues Gonçalves, Pablo; Grangeiro, Thalles Barbosa; Grattapaglia, Dario; Grisard, Edmundo Carlos; Seixas Hanna, Ebert; Neto Jardim, Silvia; Laurino, Jomar; Tenório Leoi, Lélia Cristina; Lima, Lucymara Fassarella Agnez; Loureiro, Maria de Fatima; Catanho Pereira de Lyra, Maria do Carmo; França Madeira, Humberto Maciel; Manfio, Gilson Paulo; Queiroz Maranhão, Andrea; Santos Martins, Wellington; Zingaretti di Mauro, Sônia Marli; Batistuzzo de Medeiros, Silvia Regina; De Vasconcellos Meissner, Rosely; Martins Moreira, Miguel Angelo; Do Nascimento, Fabricia Ferreira; Nicolás, Marisa Fabiana; Germano Oliveira, Jaquelline; Costa Oliveira, Sergio; Cury Paixão, Roger Ferreira; Alves Parente, Juliana; De Oliveira Pedrosa, Fabio; Junho Penat, Sergio Danilo; Odair Pereira, José; Pereira, Maristela; Rodrigues Costa Pinto, Luciana Santos; Da SilvaPinto, Luciano; Rebelo Porto, Jorge Ivan; Porto Potrich, Deise; Ramalho-Neto, Cicero Eduardo; Moreira Reis, Alessandra Maria; Um Rigo, Liu; Rondinelli, Edson; Pedraça do Santos, Elen Bethleen; Santos, Fabricio R.; Cruz Schneider, Maria Paula; Seuanez, Hector N.; Rodrigues Silva, Ana Maria; Da Costa Da Silva, Artur Luiz; Wanderlei Silva, Denise; Silva, Rosane; De Carmo Simões, Isabella; Simon, Daniel; De Almeida Soares, Célia Maria; Ascenço Soares, Renata de Bastos
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

27/05/2014

27/05/2014

30/09/2003

Resumo

Chromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism. The genome also contains extensive but incomplete arrays of ORFs coding for proteins associated with mammalian pathogenicity, possibly involved in the occasional but often fatal cases of human C. violaceum infection. There is, in addition, a series of previously unknown but important enzymes and secondary metabolites including paraquat-inducible proteins, drug and heavy-metal-resistance proteins, multiple chitinases, and proteins for the detoxification of xenobiotics that may have biotechnological applications.

Formato

11660-11665

Identificador

http://dx.doi.org/10.1073/pnas.1832124100

Proceedings of the National Academy of Sciences of the United States of America, v. 100, n. 20, p. 11660-11665, 2003.

0027-8424

http://hdl.handle.net/11449/67418

10.1073/pnas.1832124100

2-s2.0-0141758343

Idioma(s)

eng

Relação

Proceedings of the National Academy of Sciences of the United States of America

Direitos

closedAccess

Palavras-Chave #bacterial enzyme #bacterial protein #carrier protein #chitinase #heavy metal #paraquat #adaptation #bacterial genome #biotechnology #cell motility #Chromobacterium #chromobacterium violaceum #detoxification #energy metabolism #gene sequence #membrane transport #nonhuman #nucleotide sequence #open reading frame #pathogenicity #priority journal #signal transduction #stress #xenobiotic metabolism #Adaptation, Physiological #Genome, Bacterial #Molecular Sequence Data #Open Reading Frames #Bacteria (microorganisms) #Chromobacterium violaceum #Mammalia #Negibacteria #Prokaryota
Tipo

info:eu-repo/semantics/article