An animal model for the study of Chamomilla in stress and depression: pilot study


Autoria(s): Gordinho Pinto, Sandra Augusta; Bohland, Elisabeth; de Paula Coelho, Cidell; de Azevedo Morgulis, Maria Silvia Furquim; Bonamin, Leon Villano
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/07/2008

Resumo

The behavioral and hematological effects of treatment with Chamomilla 6cH in mice subjected to experimental stress are described. Swiss mice were randomly divided into pairs, one animal was inoculated with Ehrlich's tumor, the other was treated daily with Chamomilla 6cH or control or received no treatment. After 7 days, the animals were observed in an open-field arena and blood samples taken. Mice who cohabitated with a sick cage-mate showed a decrease in their general activity, but those treated with Chamomilla 6cH were less severely affected (p = 0.0426). No hematologicall changes were observed.In a second experiment, the forced swimming test was applied to mice pre-treated with Chamomilla 6cH, controls were: water, 10% ethanol or amitriptyline. Only the amitriptyline and ethanol treated groups showed significant excitatory behavior (p = 0.0020), Chamomilla 6cH treated animals' scores intermediate between water control and ethanol or amitriptyline. A decrease in the leukocyte count was observed in the amitriptyline and Chamomilla 6cH treated groups (p = 0.039). These data suggest that treatment with Chamomilla 6cH is related to the recovery of basal behavioral conditions in mice subjected to stressful conditions.

Formato

141-144

Identificador

http://dx.doi.org/10.1016/j.homp.2008.04.001

Homeopathy. Oxford: Elsevier B.V., v. 97, n. 3, p. 141-144, 2008.

1475-4916

http://hdl.handle.net/11449/41763

10.1016/j.homp.2008.04.001

WOS:000258580400006

Idioma(s)

eng

Publicador

Elsevier B.V.

Relação

Homeopathy

Direitos

closedAccess

Palavras-Chave #Chamomilla #homeopathy #behavior #neuro-immune-modulation
Tipo

info:eu-repo/semantics/article