Calcium-Independent Membrane Damage by Venom Phospholipases A(2)
| Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
|---|---|
| Data(s) |
20/05/2014
20/05/2014
01/08/2009
|
| Resumo |
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Many snake venom phospholipase A(2)s (vPLA(2)s) present biological effects that are independent of hydrolytic activity. Here we review the evidence for the calcium-independent membrane damaging activity of vPLA(2)s, the possible relevance of this activity on their biological effects, and models for the mechanism of membrane permeabilization by these proteins. |
| Formato |
877-886 |
| Identificador |
http://eurekaselect.com/84727/article Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 8, p. 877-886, 2009. 0929-8665 http://hdl.handle.net/11449/39745 WOS:000268890600004 |
| Idioma(s) |
eng |
| Publicador |
Bentham Science Publ Ltd |
| Relação |
Protein and Peptide Letters |
| Direitos |
closedAccess |
| Palavras-Chave | #Membrane permeabilization #molecular mechanism #micelle nucleation |
| Tipo |
info:eu-repo/semantics/article |
