BIOACTIVE AND OTHER PIPERIDINE ALKALOIDS FROM CASSIA-LEPTOPHYLLA
| Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
|---|---|
| Data(s) |
20/05/2014
20/05/2014
22/05/1995
|
| Resumo |
Four new piperidine alkaloids, leptophyllin A (4), 3-acetylleptophyllin A (5), leptophyllin B (8), and (-)-spectaline (1), and 3 known piperidine alkaloids, (-)-spectalinine (2), canavaline (3), and iso-6-canavaline (7), were isolated by a bioassay-guided fractionation of a leaf extract of Cassia leptophylla. The alkaloids 1 - 3 were active in a mechanism-based DNA-modifying yeast assay and 2 was moderately active in Vero monkey and Chinese hamster ovary cell cytotoxicity assays. |
| Formato |
5929-5934 |
| Identificador |
http://dx.doi.org/10.1016/0040-4020(95)00254-6 Tetrahedron. Oxford: Pergamon-Elsevier B.V., v. 51, n. 21, p. 5929-5934, 1995. 0040-4020 http://hdl.handle.net/11449/37782 10.1016/0040-4020(95)00254-6 WOS:A1995QZ65600001 |
| Idioma(s) |
eng |
| Publicador |
Elsevier B.V. |
| Relação |
Tetrahedron |
| Direitos |
closedAccess |
| Tipo |
info:eu-repo/semantics/article |
