Voltammetric assay of albendazole in pharmaceutical dosage forms


Autoria(s): de Oliveira, M. F.; Stradiotto, Nelson Ramos
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/01/2001

Resumo

A simple, rapid inexpensive voltammetric method have been developed for the quantitative determination of albendazole (ABZ) as the pure assay, by direct dissolution of commercial tablets in HCl solutions. Studies with linear sweep (LSV), square-wave (SWV) and differential pulse voltammetry (DPV) were carried out ABZ in aqueous medium at a glassy carbon electrode. A well defined irreversible oxidation peak current was obtained at 1,00V vs. SCE. The method permits a precise quantitative determination of ABZ using the standard addition method. The detection limits for the three voltammetric techniques were found to be 3.0 x 10(-5) M (LSV), 6.2 x 10(-5) M (SWV) and 4.0 x 10(-5) M (DPV).

Formato

377-387

Identificador

http://dx.doi.org/10.1081/AL-100102580

Analytical Letters. New York: Marcel Dekker Inc., v. 34, n. 3, p. 377-387, 2001.

0003-2719

http://hdl.handle.net/11449/35875

10.1081/AL-100102580

WOS:000170042200005

Idioma(s)

eng

Publicador

Marcel Dekker Inc

Relação

Analytical Letters

Direitos

closedAccess

Palavras-Chave #albendazole #differential pulse #square wave #linear sweep
Tipo

info:eu-repo/semantics/article