Physicochemical properties of sildenafil citrate (Viagra) and sildenafil base
| Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
|---|---|
| Data(s) |
20/05/2014
20/05/2014
01/10/2003
|
| Resumo |
Sildenafil citrate (Viagra) [I] and sildenafil base [II] are easily and unequivocally characterized by a set of physicochemical methods that include X-ray diffractometry, infrared spectroscopy, and thermal analysis. Monoclinic lattice constants: [I]: a = 26.98 Angstrom; b = 11.95 Angstrom; c = 16.68 Angstrom; beta = 106.97degrees. [II]: a = 8.66 Angstrom; b = 34.27 Angstrom; c = 8.93 Angstrom; beta = 96.63'. Both compounds decompose at 189.4degreesC [I] and 251.9degreesC [II]. Densities and refractive indices are given. (C) 2003 Wiley-Liss, Inc. |
| Formato |
2140-2143 |
| Identificador |
http://dx.doi.org/10.1002/jps.10469 Journal of Pharmaceutical Sciences. Hoboken: John Wiley & Sons Inc., v. 92, n. 10, p. 2140-2143, 2003. 0022-3549 http://hdl.handle.net/11449/33046 10.1002/jps.10469 WOS:000185692500021 |
| Idioma(s) |
eng |
| Publicador |
Wiley-Blackwell |
| Relação |
Journal of Pharmaceutical Sciences |
| Direitos |
closedAccess |
| Palavras-Chave | #Viagra #sildenafil citrate #sildenafil base #bioinorganic chemistry |
| Tipo |
info:eu-repo/semantics/article |
