Histological and immunological reaction of cattle skin to first-instar larvae of Dermatobia hominis


Autoria(s): OliveiraSequeira, TCG; Sequeira, Julio Lopes; Schmitt, F. L.; DeLello, E.
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/10/1996

Resumo

Six cattle that had earlier exposure to Dermatobia hominis were infested experimentally with first-instar larvae of the parasite. Skin biopsies taken at intervals were studied in wax and in plastic sections. The avidin-biotin-peroxidase method was used to detect the presence and localization of host immunoglobulins (Igs) G and M and antigens of first and second instar larvae of Dermatobia hominis. The larvae penetrated actively through the skin and migrated towards the subcutaneous tissues. The great numbers of eosinophils suggest that they are the most important cell in mediating damage to D.hominis larvae. The immunoglobulins bound only to dead or moulting larvae in which access to binding sites may have been altered. This could represent a morphological manifestation of a mechanism that protects larvae from the host immune response. Large amounts of soluble antigens detected along the fistulous tract may be important in the maintenance of this tract by disturbing the normal cicatrization process.

Formato

323-330

Identificador

http://dx.doi.org/10.1111/j.1365-2915.1996.tb00752.x

Medical and Veterinary Entomology. Oxford: Blackwell Science Ltd, v. 10, n. 4, p. 323-330, 1996.

0269-283X

http://hdl.handle.net/11449/31613

10.1111/j.1365-2915.1996.tb00752.x

WOS:A1996WC13900004

Idioma(s)

eng

Publicador

Blackwell Science

Relação

Medical and Veterinary Entomology

Direitos

closedAccess

Palavras-Chave #Dermatobia hominis #cattle #eosinophils #basophils #mast cells #immuno-histochemistry #antigens #immunoglobulins
Tipo

info:eu-repo/semantics/article