Relative antioxidant activity of Brazilian medicinal plants for gastrointestinal diseases


Autoria(s): Bonacorsi, Cibele; da Fonseca, Luiz Marcos; Raddi, Maria Stella G.; Kitagawa, Rodrigo R.; Sannomiya, Miriam; Vilegas, Wagner
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

16/09/2011

Resumo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

The free radical scavenging capacity of Brazilian medicinal plants and some of their constituents was examined in vitro using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) quantitative assay. Twelve medicinal plants, used to treat gastrointestinal disorders (Alchornea glandulosa, Alchornea triplinervia, Anacardium humile, Byrsonima crassa, Byrsonima cinera, Byrsonima intermedia, Davilla elliptica, Davilla nitida, Mouriri pusa, Qualea grandiflora, Qualea parviflora and Qualea multiflora), were selected because they showed antiulcerogenic activity in previous studies. The radical scavenging methanolic extracts activity demonstrated to be dose-dependent. The efficient concentration, which represents the amount of the antioxidant able of decrease the initial DPPH radical by 50%, vary from < 5 to 17.2 mu g/ml. The lowest efficient concentration values among the analyzed plant were shown by A. humile, B. crassa and Q. parviflora. Purified phenolic compounds (amentoflavone, (+)-catechin, methyl gallate, quercetin 3-O-alpha-L-arabinopyranoside, and quercetin 3-O-beta-D-galactopyranoside) were also tested and the greatest antioxidant activities were obtained with (+)-catechin and methyl gallate, similar to quercetin, a phenolic compound used as standard.

Formato

4511-4518

Identificador

http://www.academicjournals.org/jmpr/pdf/pdf2011/16Sept/Bonacorsi%20et%20al.pdf

Journal of Medicinal Plants Research. Victoria Island: Academic Journals, v. 5, n. 18, p. 4511-4518, 2011.

1996-0875

http://hdl.handle.net/11449/26400

WOS:000299778500019

WOS000299778500019.pdf

Idioma(s)

eng

Publicador

Academic Journals

Relação

Journal of Medicinal Plants Research

Direitos

openAccess

Palavras-Chave #Brazilian medicinal plants #antioxidant activity #2,2-diphenyl-1-picrylhydrazyl (DPPH) #gastric ulcers
Tipo

info:eu-repo/semantics/article