Evaluation of different media for the production of cephalosporins by Streptomyces clavuligerus ATCC 27064


Autoria(s): Antonio, Tatiana; Bellão, Carolina; Corrêa, Tatiana; Cavallieri, André Pastrelo; Badino, Alberto Colli; Araujo, Maria Lucia Gonsales da Costa
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/12/2012

Resumo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Processo FAPESP: 08/52819-5

Processo FAPESP: 08/03579-1

Processo FAPESP: 05/55079-4

The aim of this work was to compare the composition of a complex and soluble culture medium to eight other media described in the literature through the batch cultivation in a conventional bench-scale bioreactor for the production of cephamycin C by a wild strain of Streptomyces clavuligerus. The proposed medium resulted in an antibiotic production 1.5 to 7.5 times higher than the other culture media.

Formato

819-825

Identificador

http://dx.doi.org/10.1590/S1516-89132012000600003

Brazilian Archives of Biology and Technology. Brazilian Archives of Biology and Technology, v. 55, n. 6, p. 819-825, 2012.

1516-8913

http://hdl.handle.net/11449/25248

10.1590/S1516-89132012000600003

S1516-89132012000600003

WOS:000313343000003

S1516-89132012000600003.pdf

Idioma(s)

eng

Publicador

Brazilian Archives of Biology and Technology

Relação

Brazilian Archives of Biology and Technology

Direitos

openAccess

Palavras-Chave #β-lactam antibiotic #Streptomyces clavuligerus #lysine metabolism #complex medium
Tipo

info:eu-repo/semantics/article