Measurement of the nonlinear optical response of low-density lipoprotein solutions from patients with periodontitis before and after periodontal treatment: evaluation of cardiovascular risk markers


Autoria(s): Monteiro, Andrea M.; Jardini, Maria Aparecida Neves; Giampaoli, Viviana; Alves, Sarah; Figueiredo Neto, Antonio M.; Gidlund, Magnus
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/11/2012

Resumo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The Z-Scan (ZS) technique in the thermal regime has been used to measure the nonlinear optical response of low-density lipoprotein (LDL). The ZS technique is carried out in LDL from 40 patients with chronic periodontitis before and after three, six, and 12 months of periodontal treatment. Clinical parameters such as probing depths, bleeding on probing, total and differential white blood cells counts, lipid profiles, cytokine levels, and antibodies against oxidized LDL are also determined and compared over time. Before the treatment, the ZS experimental results reveal that the LDL particles of these patients are heavily modified. Only after 12 months of the periodontal treatment, the ZS results obtained reveal behavioral characteristics of healthy particles. This conclusion is also supported by complementary laboratorial analysis showing that the periodontal treatment induces systemic changes in several inflammatory markers. (C) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.11.115004]

Formato

7

Identificador

http://dx.doi.org/10.1117/1.JBO.17.11.115004

Journal of Biomedical Optics. Bellingham: Spie-soc Photo-optical Instrumentation Engineers, v. 17, n. 11, p. 7, 2012.

1083-3668

http://hdl.handle.net/11449/22727

10.1117/1.JBO.17.11.115004

WOS:000314502700011

WOS000314502700011.pdf

Idioma(s)

eng

Publicador

Spie-soc Photo-optical Instrumentation Engineers

Relação

Journal of Biomedical Optics

Direitos

closedAccess

Palavras-Chave #Z-scan #nonlinear #atherosclerosis #inflammation #oral health #oxLDL #periodontitis
Tipo

info:eu-repo/semantics/article