Porous titanium for biomedical applications: An experimental study on rabbits
Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
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Data(s) |
20/05/2014
20/05/2014
01/03/2010
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Resumo |
Objective: The aim of this study was to carry out an in vivo assessment of bone ingrowth in two different types of porous titanium -the first being completely porous, and the second with a porous surface and dense nucleus, manufactured by powder metallurgy- and to evaluate their mechanical properties. Study design: Ten scaffolds from each group were submitted to metallographic analysis and compression tests. Next, two scaffolds of each type were inserted into 14 rabbits, which were sacrificed 8 weeks after surgery. The samples were submitted for histological examination. Results: Metallographic analysis revealed interconnected pores, and the average interconnected pore diameter was about 360 mm, with 36% total porosity. The totally porous titanium samples and the titanium samples with porous surface and dense nucleus showed an average compressive strength of 16.19 MPa and 69.27 MPa, respectively. After 8 weeks, the animals showed bone ingrowth, even into the most internal pores. Conclusions: The pore morphology was effective in permitting bone ingrowth in both groups. Titanium scaffolds with a porous surface and dense nucleus showed the best mechanical properties and most adequate interface. |
Formato |
E407-E412 |
Identificador |
http://dx.doi.org/10.4317/medoral.15.e407 Medicina Oral Patologia Oral Y Cirugia Bucal. Valencia: Medicina Oral S L, v. 15, n. 2, p. E407-E412, 2010. 1698-4447 http://hdl.handle.net/11449/22643 10.4317/medoral.15.e407 WOS:000276236500023 |
Idioma(s) |
eng |
Publicador |
Medicina Oral S L |
Relação |
Medicina Oral Patologia Oral y Cirugia Bucal |
Direitos |
openAccess |
Palavras-Chave | #Porosity #osseointegration #titanium #mechanical properties #biomedical |
Tipo |
info:eu-repo/semantics/article |