B-cell lymphoblastic lymphoma in the maxilla of a child: A rare case report


Autoria(s): Cavalcante, A. S. R.; Anbinder, A. L.; Pontes, E. M.; Carvalho, Y. R.
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/12/2009

Resumo

Lymphoblastic lymphoma is a malignant neoplasia that originates from B or T lymphocyte precursors and rarely occurs in the mouth. The authors report a rare case of B-cell lymphoblastic lymphoma in the maxilla of a child. Clinical examination revealed facial asymmetry with a swelling of the right maxilla, covered by healthy mucosa and painful to palpation. Radiographic examination revealed a poorly defined radiolucent lesion. Based on the hypothesis of malignant neoplasia of hematopoietic origin, an incisional biopsy was performed. Histological examination revealed malignant neoplasia with proliferation of monomorphic, lymphoid cells. Immunohistochemical staining was positive for leucocyte common antigen (LCA), CD 10, CD20, CD79, and terminal deoxynucleotidyl transferase (TdT). After the diagnosis of B-cell lymphoblastic lymphoma, the patient underwent chemotherapy, but died of leukoencephalopathy and demyelinization caused by high doses of methotrexate.

Formato

1326-1330

Identificador

http://dx.doi.org/10.1016/j.ijom.2009.07.010

International Journal of Oral and Maxillofacial Surgery. Edinburgh: Churchill Livingstone, v. 38, n. 12, p. 1326-1330, 2009.

0901-5027

http://hdl.handle.net/11449/22626

10.1016/j.ijom.2009.07.010

WOS:000273103800018

Idioma(s)

eng

Publicador

Churchill Livingstone

Relação

International Journal of Oral and Maxillofacial Surgery

Direitos

closedAccess

Palavras-Chave #lymphoma #b-cell #immunophenotyping #maxillary neoplasms #children
Tipo

info:eu-repo/semantics/article